Haider Behbehani
Kuwait University, Kuwait
Biography
An efficient highly convenient synthesis of polysubstituted pyridine derivatives was established via the reaction of N-(benzothiazol-2-yl)-2-cyanoacetamides with an assortment of arylidene malononitrile or arylidene ethyl cyanoacetate in the presence of L-Proline as efficient organocatalyst for such type of ultrasonic-mediated Michael addition. The mechanistic pathway and the factors affecting this reaction were also established. The main characteristics of this procedure are high yields, utilizing a cost-effective catalyst, ease of work-up and purification ways.